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  <xs:element id="spsc_DeferredStockUnitsMember" abstract="true" name="DeferredStockUnitsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_ScheduleOfSupplementalBalanceSheetInformationRelatedToLeasesTableTextBlock" abstract="false" name="ScheduleOfSupplementalBalanceSheetInformationRelatedToLeasesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="spsc_ScheduleOfAccountingPoliciesLineItems" abstract="true" name="ScheduleOfAccountingPoliciesLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="spsc_InterTradeSystemsIncMember" abstract="true" name="InterTradeSystemsIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_DeferredCostsAmortized" abstract="false" name="DeferredCostsAmortized" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="spsc_InternallyDevelopedSoftwareMember" abstract="true" name="InternallyDevelopedSoftwareMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_MaximumRecognitionPeriodForMiscellaneousOneTimeFee" abstract="false" name="MaximumRecognitionPeriodForMiscellaneousOneTimeFee" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="spsc_DeferredCommissionExpectedAmortizationPeriod" abstract="false" name="DeferredCommissionExpectedAmortizationPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="spsc_TIEKinetixHoldingBVMember" abstract="true" name="TIEKinetixHoldingBVMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="spsc_ShareBasedCompensationArrangementByShareBasedPaymentAwardStockPlanOfferingPeriod" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardStockPlanOfferingPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="spsc_RestrictedStockUnitsAndDeferredStockUnitsMember" abstract="true" name="RestrictedStockUnitsAndDeferredStockUnitsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_DeferredCostsDisclosureTextBlock" abstract="false" name="DeferredCostsDisclosureTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="spsc_IncomeTaxExpenseBenefitLineItems" abstract="true" name="IncomeTaxExpenseBenefitLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="spsc_EarningsPerShareBasicAndDilutedEPSAbstract" abstract="true" name="EarningsPerShareBasicAndDilutedEPSAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="spsc_IncomeBeforeIncomeTaxMember" abstract="true" name="IncomeBeforeIncomeTaxMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="spsc_DeferredCostsRollForward" abstract="true" name="DeferredCostsRollForward" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="spsc_DeferredRevenueAmortizedSetUpFees" abstract="false" name="DeferredRevenueAmortizedSetUpFees" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="spsc_DeferredTaxAssetsOperatingLeaseLiabilities" abstract="false" name="DeferredTaxAssetsOperatingLeaseLiabilities" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="spsc_A2022StockRepurchaseProgramMember" abstract="true" name="A2022StockRepurchaseProgramMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_OperatingLossCarryforwardExpirableUnusedAmount" abstract="false" name="OperatingLossCarryforwardExpirableUnusedAmount" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="spsc_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardReceiptDelay" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardReceiptDelay" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="spsc_ShareBasedCompensationArrangementByShareBasedPaymentAwardValuePurchasedForAward" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardValuePurchasedForAward" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="spsc_MarketableSecuritiesMember" abstract="true" name="MarketableSecuritiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_NoncashOrPartNoncashAcquisitionContingentConsiderationLiability" abstract="false" name="NoncashOrPartNoncashAcquisitionContingentConsiderationLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="spsc_RecurringRevenuesTimingOfBillingsLatestPeriod" abstract="false" name="RecurringRevenuesTimingOfBillingsLatestPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="spsc_A2021StockRepurchaseProgramMember" abstract="true" name="A2021StockRepurchaseProgramMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseForCompensation" abstract="false" name="EffectiveIncomeTaxRateReconciliationNondeductibleExpenseForCompensation" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="spsc_DeferredCostsAndAmortizationTableTextBlock" abstract="false" name="DeferredCostsAndAmortizationTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="spsc_AnalyticsMember" abstract="true" name="AnalyticsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_OfficeEquipmentAndFurnitureMember" abstract="true" name="OfficeEquipmentAndFurnitureMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_ScheduleOfStockholdersEquityTable" abstract="true" name="ScheduleOfStockholdersEquityTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="spsc_PerformanceShareUnitsRestrictedStockUnitsRestrictedStockAwardsAndDeferredStockUnitsMember" abstract="true" name="PerformanceShareUnitsRestrictedStockUnitsRestrictedStockAwardsAndDeferredStockUnitsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_GeographicInformationTextBlock" abstract="false" name="GeographicInformationTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="spsc_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentAccountsReceivable" abstract="false" name="BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentAccountsReceivable" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="spsc_FulfillmentMember" abstract="true" name="FulfillmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_SetUpFeesMember" abstract="true" name="SetUpFeesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_ScheduleOfSupplementalCashFlowInformationRelatedToLeasesTableTextBlock" abstract="false" name="ScheduleOfSupplementalCashFlowInformationRelatedToLeasesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="spsc_EmployeeStockPurchasePlanMember" abstract="true" name="EmployeeStockPurchasePlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_RevenueRecognitionTable" abstract="true" name="RevenueRecognitionTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="spsc_CashPaidForAmountsIncludedInMeasurementOfLeaseLiabilitiesAbstract" abstract="true" name="CashPaidForAmountsIncludedInMeasurementOfLeaseLiabilitiesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="spsc_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherAssets" abstract="false" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherAssets" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="spsc_DeferredRevenueInvoicedSetUpFees" abstract="false" name="DeferredRevenueInvoicedSetUpFees" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="spsc_DeferredTaxLiabilitiesPropertyPlantAndEquipmentAndOtherFiniteLivedAssets" abstract="false" name="DeferredTaxLiabilitiesPropertyPlantAndEquipmentAndOtherFiniteLivedAssets" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="spsc_DeferredCostsIncurred" abstract="false" name="DeferredCostsIncurred" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="spsc_RevenueRecognitionLineItems" abstract="true" name="RevenueRecognitionLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="spsc_ContractTermMaximum" abstract="false" name="ContractTermMaximum" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="spsc_OneTimeRevenuesMember" abstract="true" name="OneTimeRevenuesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_IncreaseDecreaseInOperatingLeases" abstract="false" name="IncreaseDecreaseInOperatingLeases" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="spsc_TreasuryStockUnusedAndExpiredRepurchaseValue" abstract="false" name="TreasuryStockUnusedAndExpiredRepurchaseValue" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="spsc_DeferredRevenueArrangementRollForward" abstract="true" name="DeferredRevenueArrangementRollForward" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="spsc_ComputerEquipmentAndSoftwareMember" abstract="true" name="ComputerEquipmentAndSoftwareMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_RecurringRevenuesMember" abstract="true" name="RecurringRevenuesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_BusinessDescriptionPolicyPolicyTextBlock" abstract="false" name="BusinessDescriptionPolicyPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="spsc_ScheduleOfStockholdersEquityLineItems" abstract="true" name="ScheduleOfStockholdersEquityLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="spsc_ScheduleOfPercentageOfPropertyAndEquipmentNetTableTableTextBlock" abstract="false" name="ScheduleOfPercentageOfPropertyAndEquipmentNetTableTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="spsc_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfOfferingPeriods" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfOfferingPeriods" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="spsc_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentOtherAssets" abstract="false" name="BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentOtherAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="spsc_GCommerceIncMember" abstract="true" name="GCommerceIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="spsc_LesseeOperatingLeaseAreaOfLeasedSpace" abstract="false" name="LesseeOperatingLeaseAreaOfLeasedSpace" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:areaItemType"/>
  <xs:element id="spsc_IncomeTaxExpenseBenefitTable" abstract="true" name="IncomeTaxExpenseBenefitTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
</xs:schema>
